Master’s Degree Awarded to Ms. Naseem Amer in Pharmacology and Therapeutics

Ms. Naseem Tawfiq Yahya Amer was awarded a Master’s Degree in Pharmacology and Therapeutics for her thesis titled: Evaluation of Analgesic Effect of Capparis cartilaginea Leaf Extract and Investigation of Its Potential Mechanism of Action, which was submitted to the Department of Pharmacology and Therapeutics, Faculty of Medicine and Health Sciences – Sana’a University. The MA defense was held on Monday, June 15, 2026 .
The MA Viva-voce Committee, which was formed based on a resolution issued by the Graduate Studies and Scientific Research Council, consisted of the following:
# |
Committee Members |
Designation |
Position |
1 |
Assoc. Prof. Salwa Mohammed Rajeh |
Internal Examiner |
Chair |
2 |
Assoc. Prof. Hassan Mohammed Al-Mahbashi |
Main Supervisor |
Member |
3 |
Assoc. Prof. Ali Abdullah Al-Yahwi |
External Examiner |
Member |
The thesis aimed to:
-
Evaluate the analgesic activity of Capparis cartilaginea leaf extract using experimental animal models.
-
Investigate its potential mechanism of action through molecular docking and network pharmacology approaches.
-
Explore the therapeutic potential of the plant’s bioactive compounds as candidates for future pain-management therapies.
The study yielded several key findings summarized as follows:
-
The leaf extract demonstrated significant and pronounced analgesic activity in the experimental models.
-
The extract appears to exert its effects through multiple pharmacological targets and pathways, enhancing its potential therapeutic efficacy.
-
The active compound Hepta-1 exhibited promising pharmacological properties and may serve as a potential lead compound for the development of future analgesic drugs.
In light of these findings, the researcher recommended the following:
-
Conducting further advanced pharmacological and molecular investigations to validate the efficacy of the active compounds and clarify their mechanisms of action.
-
Isolating and characterizing the plant’s bioactive constituents and examining their pharmacological and chemical properties in greater detail.
-
Expanding preclinical and clinical research to explore the therapeutic applications of these compounds and support the development of novel analgesic agents.
The defense session was attended by a number of academics, researchers, students, colleagues, and the researcher’s family.





