Personal Information:

Riyadh Saif-Ali

Biochemistry Department Faculty of Medicine, Sana’a University, Yemen

reyadh70@su.edu.ye

Tel +967736292923,

+967773538387

Summary:

Riyadh is currently associated professor in Biochemistry Department, Faculty of Medicine, Sana’a University. Riyadh received his PhD in Molecular Medicine from the UKM Medical Molecular Biology Institute, University Kebangsaan Malaysia on November 2009, he joined Molecular Medicine Department, Faculty of Medicine, University of Malaya as a postdoctoral research fellow on March 19, 2010 until August 31 2012. In addition, Riyadh worked as the head of the Biochemistry Department, Faculty of Medicine, Sana’a University.

He has published more than 45 scholarly papers in global fields and possesses expertise in various molecular genetic techniques including RT-PCR and PCR, DNA Sequencing, Microsatellite, Gene Expression, Genotyping, Restriction Fragment Length Polymorphism (RFLP), dHPLC and Copy Number Variations (CNVs). In addition, Riyadh had opportunity to work in Cell Culture Techniques, Microbiology, Haematology and Clinical Chemistry Laboratory. Riyadh has a good experience in analysing data by SPSS and different types of genetic software.

Please refer to the CV of more details.

Education:

PhD in Molecular Medicine, UKM Medical Molecular Biology Institute, University Kebangsaan Malaysia (2005-2009)

Master in Clinical Biochemistry, Faculty of Medicine, Sana’a University, Yemen (1998-2001)

Bachelor of Medical Laboratory, Faculty of Medicine, Sana’a University, Yemen (1990-1993)

Experience:

Associate Prof, Biochemistry Dep. Faculty of Med, Sana’a University, Yemen, June, 2015 till now

Molecular Medicine Consultant, 48 Hospital, Sana’a, Yemen, Nov 2018- Jan 2020

Dean of the Faculty of Laboratory Medicine, 21 University, Sana’a, Yemen, June 2016-, June 2017

Head of the Biochemistry Department, Faculty of Medicine, Sana’a University, Yemen, Jan 2013 – Sep 2013

Assistant Professor, Biochemistry Dep. Faculty of Med, Sana’a University, Yemen, since 2009 – 2014

Postdoctoral Research Fellow, Molecular Medicine Dep. Faculty of medicine, University Malaya, Malaysia, 2010- 2012

Lecturer, Biochemistry Dep. Faculty of Med, Sana’a University, 2001-2004

Tutor, Biochemistry Dep. Faculty of Med, Sana’a University, 1996-2001

Laboratory Manager in Al-Sabeen Hospital, Sana’a Yemen, 1995-1996

Conferences and Workshops:

Wahib M. Atroosh, Hesham M. Al-Mekhlafi, Mohammed A.K. Mahdy, Riyadh Saif-Ali and Johari Surin. 2011. Molecular markers for chloroquine-resistant Plasmodium falciparum malaria in Peninsular Malaysia. Joint International Tropical Medicine Meeting 2010 (JITMM 2010), and the International Malaria Colloquium 2010 (IMC 2010). 1-3 December 2010, Bangkok.

Saif-Ali R, Wan Ngah W Z, Mazlan M, Harun R,  Siti Harnida, Kamaruddin N A, Jamal A R (2007). Hepatocyte Nuclear Factor 4 alpha Polymorphisms in Type 2 Diabetes Mellitus. MJMS (14) Sup 1, OBT-7.

Sami Abdo Radman Al-Dubai (presenter), Ahmad Munir Q, Riyadh Saif-Ali, Amirah Tan  A,  Ganasegeran K,  Jalal Ibrahim Shawqi H, Mohammed Faez B, Awareness and knowledge of breast cancer and mammography among a group of Malaysian women in Shah Alam. First International Public Health Conference and 18th National Public Health Colloquium. The Legend Hotel, Kuala Lumpur, 27th September 2011.

Wahib M Atroosh, Hesham M Al-Mekhlafi, Mohammed AK Mahdy, Riyadh Saif-Ali,
Nazeh M Al-abd, Abdulsalam MQ Al-Mekhlafi, Nabil A Nasr and Johari Surin.
Genetic diversity of Plasmodium falciparum isolated from Peninsular Malaysia based on msp1 and msp2 genes. 47th Annual Conference of the Malaysian Society of Parasitology and Tropical Medicine (MSPTM). 3-4 March 2011. International Medical University. Kuala Lumpur, Malaysia.

Saif-Ali R, Jamal A R , Mazlan M, Harun R,  Siti Harnida, Kamaruddin N A, Wan Ngah W Z (2008). Hepatocyte Nuclear Factor 4 alpha and Insulin Resistance. Oral presentation at the 2nd Health and Medical Sciences Conference. USM, Penang, Malaysia.

Saif-Ali R, Wan Ngah W Z, Mazlan M , Harun R,  Siti Harnida, Kamaruddin N A, Jamal A R (2007). Comparing Hepatocyte Nuclear Factor 4 alpha Polymorphisms among Malay and Chinese with Type 2 Diabetes Mellitus. Oral presentation at the 2nd regional Conference on Molecular Medicine. The Legend Hotel, Kuala Lumpur, Malaysia.

Saif-Ali R, Wan Ngah W Z, Mazlan M, Harun R,  Siti Harnida, Kamaruddin N A, Jamal A R (2006). Prevalence of Metabolic Syndrome of Type 2 Diabetes Patients in Malaysia Defined by International Diabetes Federation and National Cholesterol Education  Program. Oral presentation at the International Conference: Exploring New Frontiers in Medicine and Health (ICFMH) 2006, 1st-2nd Aug 2006, Putra World Trade Centre, Kuala Lumpur.

Sami Abdo Radman Al-Dubai (presenter), Ahmad Munir Q, Riyadh Saif-Ali, Amirah Tan  A,  Ganasegeran K,  Jalal Ibrahim Shawqi H, Mohammed Faez B, Awareness and knowledge of breast cancer and mammography among a group of Malaysian women in Shah Alam. First International Public Health Conference and 18th National Public Health Colloquium. The Legend Hotel, Kuala Lumpur, 27th September 2011.

Saif-Ali R, Wan Ngah W Z, Mazlan M , Harun R,  Siti Harnida, Kamaruddin N A, Jamal A R (2006). Polymorphism in Promoter and Non-Coding Region of Hepatocyte Nuclear Factor-4 alpha Gene Predicts Susceptibility to Type 2 Diabetes in Malaysia. Poster presentation at the 5th International Seminar: Asian Network of Research on Antidiabetic Plants (ANRAP) 8-10th Nov 2006 Cititel, Midvalley City,  Kuala Lumpur, Malaysia.

Saif-Ali R, Jada S R, Stanslas J, Saad S, Lajis N H, Hamzah A S: Antitumour Activities of Synthetic Derivatives of APAG-1. Poster Presentation at the 19th Annual Seminar and Workshop of the Malaysian Natural Product Society. 13-16th October 2003 Faculty of Science, University of Malaysia, Kuala Lumpur, Malaysia

Research and scientific papers:

Ahmed F, Molham A-H, Al-Zabedi E, Saif-Ali R (2021). Impact of triglycerides and waist circumference on insulin resistance and β-cell function in non-diabetic first-degree relatives of type 2 diabetes. BMC Endocr. Disord. https://doi.org/10.1186/s12902-021-00788-5)

Al-Absi, B., A.-H. Molham, and R. Saif-Ali, (2021).  Plasma Lipocalin-2 and Adiponectin are Affected by Obesity Rather Than Type 2 Diabetes Mellitus per se. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 14: p. 4547.

MOHARRAM BA, AL-MAHBASHI HM, Al-Maqtari T, Saif-Ali R, A-DOAISS AA (2021) ALOE IRAFENSIS AN ENDEMIC PLANT OF YEMEN: PHYTOCHEMICAL SCREENING, ANTIBACTERIAL, ANTIOXIDANT, AND WOUND HEALING ACTIVITIES. Asian J Pharm Clin Res 14:88-94

Al-Zubairi T, Molham A-H, Saif-Ali R (2021) Latent Autoimmune Diabetes in Adults (LADA) and its Metabolic Characteristics among Yemeni Type 2 Diabetes Mellitus Patients. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 14:4223.

Saif-Ali R, Kamaruddin NA, Molham A-H, Al-Dubai SA, Ngah WZW (2020). Relationship of metabolic syndrome defined by IDF or revised NCEP ATP III with glycemic control among Malaysians with Type 2 Diabetes. Diabetology & metabolic syndrome, 12(1):1-7

Saeed W, Molham A-H, Saif-Ali R, Al-Eryani E (2020). Metabolic Syndrome and Prediabetes Among Yemeni School-Aged Children. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 13:2563.

Moharram B, Al-Doaiss A, Al-Mahbashi H, Al-Kahtani M, Alfaifi M, Elbehairi SEI, Saif-Ali R (2020). Hepatoprotective, Antioxidant and Cytotoxic Potential of Aloe niebuhriana Latex Extract from Yemen. Indian Journal of Pharmaceutical Sciences, 82(3):514-521.

Haber M, Saif-Ali R, Alhabori M, Chen Y, Platt DE, Tyler-Smith C, Xue Y (2019). Insight into the genomic history of the Near East from whole-genome sequences and genotypes of Yemenis BioRxiv, 749341

AM Othman, RM Assayaghi, HZ Al-Shami, R Saif-Ali (2019). Asymptomatic carriage of Streptococcus pyogenes among school children in Sana’a city, Yemen BMC research notes 12, 339

Mohammed, M., AL-Habori, M., Abdullateef, A., & Saif-Ali, R. (2018). Impact of Metabolic Syndrome Factors on Testosterone and SHBG in Type 2 Diabetes Mellitus and Metabolic Syndrome. Journal of diabetes research, 1-8

Lemieux AM, Nakajima M, Saif-Ali R, Al-Habori M, Dokam A, al’Absi M. (2018) Anger, anxiety, and depressive affect as predictors of stress-induced cortisol production in khat and tobacco users. Addictive behaviors, 82:195-201.

Moharram  BA, Al-Mahbashi HM, Saif-Ali R, Aqlan FA (2018). Phytochemical, anti-inflammatory, antioxidant, cytotoxic and antibacterial study of capparis cartilaginea decnefrom yemen. Int J Pharm Pharm Sci, 10: 35-44

Al-absi, Boshra, Muhammad FM Razif, Suzita M Noor, Riyadh Saif-Ali, Mohammed Aqlan, Sameer D Salem, Radwan H Ahmed, and Sekaran Muniandy. (2017) Contributions of IKZF1, DDC, CDKN2A, CEBPE, and LMO1 Gene Polymorphisms to Acute Lymphoblastic Leukemia in a Yemeni Population. Genetic Testing and Molecular Biomarkers.

Al-absi, Boshra, Suzita M Noor, Riyadh Saif-Ali, Sameer D Salem, Radwan H Ahmed, Muhammad FM Razif, and Sekaran Muniandy. (2017) Association of ARID5B gene variants with acute lymphoblastic leukemia in Yemeni children. Tumor Biology 39 (4):1010428317697573. (ISI/SCOPUS Cited Publication).

Othman AM, Abuasba NW, Saif-Ali R. (2018) Factors Associated with Post-Transplant Anemia among Renal Transplant Recipients with Functioning Grafts in Sana’a City, Yemen. Yemeni Journal for Medical Sciences, 11:24-30.

Haber M, Mezzavilla M, Bergström A, Prado-Martinez J, Hallast P, Saif-Ali R, Al-Habori M, Dedoussis G, Zeggini E, Blue-Smith J (2016) Chad Genetic Diversity Reveals an African History Marked by Multiple Holocene Eurasian Migrations. The American Journal of Human Genetics 2016, 99:1316-1324 (ISI/SCOPUS Cited Publication)

Al-Mekhlafi, Abdulsalam M, Rashad Abdul-Ghani, Samira M Al-Eryani, Reyadh Saif-Ali, and Mohammed AK Mahdy. (2016) School-based prevalence of intestinal parasitic infections and associated risk factors in rural communities of Sana’a, Yemen. Acta tropica 163:135-141. (ISI/SCOPUS Cited Publication).

Abdul-Ghani R, Mahdy MA, Saif-Ali R, Alkubati SA, Alqubaty AR, Al-Mikhlafy AA, Al-Eryani SM, Al-Mekhlafi AM, Alhaj A (2016) Glucose-6-phosphate dehydrogenase deficiency among Yemeni children residing in malaria-endemic areas of Hodeidah governorate and evaluation of a rapid diagnostic test for its detection. Malar J 15: 327 (ISI/SCOPUS Cited Publication).

Mahdy MA, Al-Mekhlafi AM, Abdul-Ghani R, Saif-Ali R, Al-Mekhlafi HM, Al-Eryani SM, Lim YA, Mahmud R (2016) First Molecular Characterization of Leishmania Species Causing Visceral Leishmaniasis among Children in Yemen. PLoS One 11: e0151265 ISI/SCOPUS Cited Publication).

Al-Hamodi Z, Saif-Ali R, IS Ismail IS, Poh,R, Ahmed RH, Muniandy S 2015. Impact of Ethnicity on the Association of Plasminogen Activator Inhibitor-1 and Tissue Plasminogen Activator Polymorphisms with Type 2 Diabetes Mellitus. Public Health Genomics 18, 30-30

Al-Henhena N, Khalifa SA, Ying RPY, Ismail S, Hamadi R, Shawter AN, Idris AM, Azizan A, Al-Wajeeh NS, Abdulla MA. (2015) Evaluation of chemopreventive potential of Strobilanthes crispus against colon cancer formation in vitro and in vivo. BMC complementary and alternative medicine, 15:419.

Al-Dubai W, Al-Ghazaly J, AL-Habori M, Saif-Ali R,  Mohammed A. 2014. Catha edulis (Khat) chewing decreases serum levels of iron, ferritin and vitamin B12 and increases folic acid Int J Vitam Nutr Res: ( ISI/SCOPUS Cited Publication).

Al-Hamodi Z, Molham ALH, Al-Meeri A and Saif-Ali R. 2014. Association of adipokines, leptin/adiponectin ratio and C-reactive protein with obesity and type 2 diabetes mellitus. Diabetology & metabolic syndrome 6: 99 ( ISI/SCOPUS Cited Publication).

Al-Hamidhi S, Mahdy MA, Idris MA, Bin Dajem SM, Al-Sheikh AA, Al-Qahtani A, Al-Hashami Z, Al-Farsi H, Al-Mekhlafi AM, Saif-Ali R, Beja-Pereira A, Babiker HA. 2014. The prospect of malaria elimination in the Arabian Peninsula: A population genetic approach.  Infect Genet Evol; 27C: 25-31. ( ISI/SCOPUS Cited Publication).

Salem SD, Saif-Ali R, Muniandy S , Al-Hamodi Z and Ismail IS. 2014. Comparison of Adults with Insulin Resistance (IR) in Latent Autoimmune Diabetes Versus IR in Glutamic Acid Decarboxylase Antibody-negative Diabetes. Ann Acad Med Singap. 43:107-112 ( ISI/SCOPUS Cited Publication).

Almagrami AA, Alshawsh MA, Saif-Ali R, Shwter A, Salem SD, Abdulla MA. 2014. Evaluation of chemopreventive effects of Acanthus ilicifolius against azoxymethane-induced aberrant Crypt Foci in the rat colon.  PLoS One; 9: e96004) (dOI:10.1371/journal.pone.0096004 (ISI/SCOPUS Cited Publication)

Al-Motarreb AL, Saif-Ali, Othman AM, Masood HA, Nassar MY. 2014. Human Leukocyte Antigen Class II Genetic Variants are Highly Associated with Rheumatic Heart Disease in Yemeni Patients. Kuwait Med J. (Accepted) (ISI/SCOPUS Cited Publication)

Salem S D, Saif-Ali R, Ismail I S, Al-Hamodi Z, and Muniandy S.2014. Contribution of

SLC30A8 variants to the risk of type 2 diabetes in a multi-ethnic population: a case control study. BMC Endocr Disord,14-2 ( doi:10.1186/1472-6823) (ISI/SCOPUS Cited Publication).

Dubai S A R, Ganasegeran K, Alwan M R, Alshagga M A, Saif-Ali R. 2013.  Factors Affecting Dengue Fever Knowledge, Attitudes and Practices Among Selected Urban, Semi-Urban And Rural Communities in Malaysia. Southeast Asian J Trop Med Public Health 44:37-49 ISI/SCOPUS Cited Publication).

Salem S D, Saif-Ali R, Ismail I S, Al-Hamodi Z, Poh R and Muniandy S. 2012. IGF2BP2 Alternative Variants Associated with Glutamic Acid Decarboxylase Antibodies Negative Diabetes in Malaysian Subjects. PlosOne 7(9):1-7) e45573 (doi:10.1371/journal.pone.0045573). (ISI/SCOPUS Cited Publication).

Dubai S A R, Ganasegeran K, Alabsi A M, Alshagga M A, Saif-Ali R. 2012. Awareness and Knowledge of Oral Cancer among University Students in Malaysia. Asian Pac. J. Cancer Prev 13, 165-168. (ISI/SCOPUS Cited Publication).

Al-Hamodi Z, Saif-Ali R, Ismail I S, Ahmed  K and Muniandy S. 2012. Effect of Plasminogen Activator Inhibitor-1 and Tissue Plasminogen Activator Polymorphisms on Susceptibility to Type 2 Diabetes in Malaysian Subjects. J Biomed Biotechnol. (doi:10.1155/2012/234937, Online, ISI/SCOPUS Cited Publication).

Saif-Ali R, Harun S, Kamaruddin N A, Al-Jassabi Sand Ngah W Z W. 2012. Association of Hepatocyte Nuclear Factor 4 alpha Polymorphisms with Type 2 Diabetes with or without Metabolic Syndrome in Malaysia. Biochem Genet. 50, 298-308. (ISI/SCOPUS Cited Publication)

Al-Hamodi Z H, Saif-Ali R, Ismail I S, Ahmed K A and Muniandy S. 2012. Plasminogen activator inhibitor-1 4G/5G polymorphism is associated with metabolic syndrome parameters in Malaysian Subjects. J Clin Biochem Nutr. (doi:10.3164/jcbn.11-48) (ISI/SCOPUS Cited Publication)

Saif-Ali R, Muniandy S, Al-Hamodi Z, Siang L C, Ahmed K A, Al-Mekhlafi A M, Ismail I S. 2011. KCNQ1 variants associate with type 2 diabetes in Malaysian Malay subjects. Ann Acad Med Singap. 40, 488-492. (ISI/SCOPUS Cited Publication)

Dubai S A R, Quresh A M, Saif-Ali R, Ganasegeran K, Alwan M R and Hadi Si J I , 2011. Awareness and Knowledge of Breast Cancer and Mammography among a Group of Malaysian Women in Shah Alam.  Asian Pac J Cancer P  12, 2531-2538 . ISI/SCOPUS Cited Publication).

Atroosh W M, Al-Mekhlafi H M, Mahdy M A K, Al-Mekhlafi A M,  Saif-Ali R and Surin J. 2011. Genetic diversity of Plasmodium falciparum isolates from Pahang, Malaysia based on MSP-1 and MSP-2 genes. Parasites Vectors 4:233,1-9 (ISI/SCOPUS Cited Publication)

Saif-Ali R, Ismail I S, Al-Hamodi Z, Al-Mekhlafi H M, Siang L C, Alabsi  A M, Muniandy S. 2011. KCNQ1 Haplotypes Associate with Type 2 Diabetes in Malaysian Chinese Subjects. International Journal of Molecular Sciences 12, 5705-5718. (ISI/SCOPUS Cited Publication)

Ali R, Alabsi AM, Ali AM, Ideris A, Omar AR, Yusoff K, Saif-Ali R. 2011. Cytolytic Effects and Apoptosis Induction of Newcastle Disease Virus Strain AF2240 on Anaplastic Astrocytoma Brain Tumor Cell Line. Neurochem Res 36: 2051-62. (ISI/SCOPUS Cited Publication)

Saif-Ali R, Harun R, Al-Jassabi S, Wan Ngah WZ. 2011. Hepatocyte nuclear factor 4 alpha P2 promoter variants associate with insulin resistance. Acta Biochim Pol 58: 179-86 (ISI/SCOPUS Cited Publication)

Ahmed KAA, Muniandy S, Ismail I S, Saif-Ali R, Alhamodi ZH. 2011. Evaluation of N -(carboxymethyl) lysine and lipid peroxidation in multiethnic Malaysian subjects with type 2 diabetes mellitus. Scientific Research and Essays 6: 1957-62 (ISI/SCOPUS Cited Publication)

Al-Hamodi Z, Ismail IS, Saif-Ali R, Ahmed KA, Muniandy S. 2011. Association of plasminogen activator inhibitor-1 and tissue plasminogen activator with type 2 diabetes and metabolic syndrome in Malaysian subjects. Cardiovasc Diabetol 10: 23(ISI/SCOPUS Cited Publication)

Al-Zubairi AS, Patimah I, Chong PP, Ahmad BA, Saif-Ali R, Abdel Wahab SI and Asmah R. 2008. Short-Term Repeated Dose Biochemical Effects of Catha edulis (Khat) Crude Extract Administration in Rats. Int. J. Trop. Med., 3 (2): 19-25. (SCOPUS Cited Publication)

Saif-Ali R, Al-Qirbi A, Al-Geiry A, M AL-H. 2003. Effect of Catha edulis on plasma glucose and C-peptide in both type 2 diabetics and non-diabetics. J Ethnopharmacol 86: 45-49 (ISI/SCOPUS Cited Publication)